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Hormones, Ageing & Longevity Claims — cover

Peptides & New Compounds · Volume 50

Hormones, Ageing & Longevity Claims

Testosterone, growth hormone and the anti-ageing industry

The Longevity Truth Guide

Core edition

  • Hormones and ageing, explained honestly
  • Separate evidence from anti-ageing hype
  • Habits proven to add healthy years
₹449 58-page PDF

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About this book

Ageing is inevitable. Selling a cure for it is big business. Clinics offer testosterone for "low energy", growth hormone for "youthfulness", and supplements and injections promising to add decades of life.

This book separates evidence from marketing. It explains how hormones change with age; when testosterone therapy is medically appropriate and when it isn't; what menopausal hormone therapy can and can't do; why growth hormone isn't an anti-ageing drug; what the science says about DHEA, NAD+, metformin, rapamycin and other "longevity" compounds; and which habits have the strongest evidence for a longer, healthier life.

A grounded guide for anyone who wants to age well — without being sold false hope.

Educational guide. It supports — never replaces — care from your doctor, and contains no doses, cycles or sources.

Inside: 23 chapters

  1. 01How Hormones Change with Age
  2. 02Low Testosterone in Men
  3. 03Testosterone Therapy
  4. 04"Low T" Clinics and Marketing
  5. 05Menopause and Hormone Therapy
  6. 06Growth Hormone
  7. 07DHEA
  8. 08The Longevity Market
  9. 09Biological Age Tests
  10. 10What Actually Works
  11. 11Muscle and Bone
  12. 12Cardiovascular Fitness
  13. 13Preventive Health Checks
  14. 14Ageing Well, Mentally
  15. 15Thyroid and Ageing
  16. 16Melatonin and Sleep in Later Life
  17. 17Skin Ageing
  18. 18The Anti-Ageing Industry
  19. 19A Weekly Healthy-Ageing Template
  20. 20Stories
  21. 21Questions People Ask
  22. 22Your Healthy Ageing Plan
  23. 23Glossary

Read the introduction

Chapter 1

How Hormones Change with Age

Normal ageing vs disease

Some hormonal decline is a normal part of ageing. The key medical question is whether a person has a condition that needs treatment — not whether their levels match those of a 25-year-old.

"Optimising" hormones to youthful levels isn't the same as treating a disease — and doesn't have the same evidence base.

Low Testosterone in Men

Male hypogonadism

A clinical condition in which the body doesn't produce enough testosterone, diagnosed through:

• Symptoms consistent with low testosterone (see below).

• Repeatedly low blood levels, usually measured in the morning on at least two occasions.

• Investigation of the cause (e.g. pituitary problems, testicular problems, medications, obesity).

Possible symptoms

Many of the less specific symptoms have other common causes: poor sleep, depression, obesity, diabetes, alcohol, stress and other illnesses.

Lifestyle factors that lower testosterone

• Obesity (especially abdominal fat).

• Poor sleep and sleep apnoea.

• Heavy alcohol use.

• Chronic stress.

• Some medicines (e.g. opioids, glucocorticoids).

• Past anabolic steroid use (Vol. 45).

Moderate evidence: Weight loss, better sleep and reduced alcohol can raise testosterone in some men with low-normal levels.

The book continues for 58 pages across 23 chapters.

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